Gero Miesenböck
Gero Miesenböck is Waynflete Professor of Physiology at the University of Oxford and a fellow of Magdalen College.[1] A native of Austria, he received his M.D. from the University of Innsbruck and undertook postdoctoral training with James Rothman.[2] Before coming to Oxford, he held faculty appointments at Memorial Sloan-Kettering Cancer Center[3] and Yale University.[4]
Miesenböck is the founder of the emerging field of optogenetics.[5][6] He has developed genetic strategies for visualizing and controlling nerve cells with light. He has invented several methods, including genetically targeted photostimulation of neurons and optical imaging of neurotransmission with synapto-pHluorin, a derivative of the green fluorescent protein.[7][8]
Miesenböck’s research on optogenetics and the nervous system of the fruit fly details the structure and function of neural circuits responsible for sensory processing, action selection, and motor pattern generation.
References
- ^ http://www.neuroscience.ox.ac.uk/directory/gero-miesenboeck Dr. Miesenböck’s Research Website at the University of Oxford
- ^ Miesenböck, G.; Rothman, J. (1995). "The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack". The Journal of cell biology 129 (2): 309–319. doi:10.1083/jcb.129.2.309. PMC 2199920. PMID 7721936. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2199920. edit
- ^ Zemelman, B. V.; Nesnas, N.; Lee, G.; Miesenbock, G. (2003). "Photochemical gating of heterologous ion channels: Remote control over genetically designated populations of neurons". Proceedings of the National Academy of Sciences 100 (3): 1352–1357. doi:10.1073/pnas.242738899. PMC 298776. PMID 12540832. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=298776. edit
- ^ Sjulson, L.; Miesenbock, G. (2008). "Rational Optimization and Imaging in Vivo of a Genetically Encoded Optical Voltage Reporter". Journal of Neuroscience 28 (21): 5582–5593. doi:10.1523/JNEUROSCI.0055-08.2008. PMC 2714581. PMID 18495892. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2714581. edit
- ^ Miesenböck, G. (2009). "The Optogenetic Catechism". Science 326 (5951): 395–399. doi:10.1126/science.1174520. PMID 19833960. edit
- ^ http://www.ted.com/talks/gero_miesenboeck.html Miesenböck speaks at TED about optogenetics
- ^ Wells, W. A. (2007). "Gero Miesenbock: Instructing the nervous system". The Journal of Cell Biology 177 (3): 374–375. doi:10.1083/jcb.1773pi. PMC 2064810. PMID 17485485. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2064810. edit
- ^ http://www.nytimes.com/2005/04/12/science/12fly.html?ex=1188014400&en=c1ca4b6a117cc3f2&ei=5070 An off-and-on switch for controlling animals?
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